Poster Presentation 33rd ASM of the Australian & New Zealand Bone & Mineral Society 2023

Quality of life in population-based women with comorbid arthritis and mood disorders (#206)

Shae E Quirk 1 2 3 , Risto Honkanen 2 3 4 , Amanda L Stuart 1 , Jeremi Heikkinen 2 3 , Julie A Pasco 1 5 , Lana J Williams 1 5 , Kara Anderson 6
  1. School of Medicine, Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Vic, Australia
  2. Institute of Clinical Medicine, Psychiatry, University of Eastern Finland, Kuopio, Finland
  3. Kuopio Musculoskeletal Research Unit (KMRU), Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
  4. Mental Health and Wellbeing Center, Kuopio University Hospital, Kuopio, Vic, Finland
  5. Barwon Health, University Hospital Geelong, Geelong, Vic, Australia
  6. Deakin University, Geelong, VIC, Australia

Background: Separately, mental and musculoskeletal disorders are leading contributors to disability worldwide. We examined the quality of life (QoL) of women with arthritis, mood disorders, and the comorbidity of these.  

 

Methods: This cross-sectional study analysed data from the Geelong Osteoporosis Study (n=840 women aged 28–95 years; 2011–2014). A history of arthritis was self-reported; lifetime mood disorders were assessed using the SCID-I/NP. QOL was measured using the WHOQOL-BREF (26-items; 5-point Likert scale); we calculated four domains: I) perceived physical health (pain & discomfort/energy & fatigue/sleep & rest/medication/mobility/activities of daily living/work capacity); II) psychological health (positive/negative feelings/self-esteem/cognition/body image/spirituality/religion); III) social health (relationships/sex/practical support); and IV) environmental health (financial resources/information/skills/recreation/leisure/home environment/access to health/social care/physical environment/transport). QoL domains were dichotomised using normative mean scores. Age-adjusted logistic regression models investigated associations between arthritis, mood disorders, and their comorbidity in relation to QOL domains.  

 

Results:

A total of 18.7% (157/840), 26.3% (221/840), and 11.01% (93/840) of women had lifetime arthritis, mood disorders, or their comorbidity (both arthritis and mood disorders), respectively.

Compared to women with no history, the odds of lower physical health QoL were increased in women with arthritis (OR=2.06; 95%CI 1.34-3.16) and mood disorders (OR=3.08; 95%CI 2.12-4.47), but the highest odds belonged to the comorbidity group (OR=6.18 95%CI 3.57-10.69). Women with mood disorders had increased odds of both lower psychological (OR=3.10; 95%CI 2.16-4.44), and social (OR=2.33; 95%CI 1.64-3.31) health QoL with the comorbidity groups having similar odds (OR=2.91; 95%CI 1.73-4.88; OR=2.80; 95%CI 1.71-4.60). Arthritis was not significantly associated with psychological or social health QoL, whereas none of the three groups were associated with environmental health QoL.  

 

Conclusion: Women with comorbid arthritis and mood disorders have disproportionately lower physical health QoL than women with no history.